Clinical Case Studies
Clinical Case Studies - AACC.org
Each month, a case and a series of questions can be emailed to interested individuals 4-6 weeks in advance of publication.
Clinical Case Studies
Short-term effects of smoking marijuana on balance in patients with multiple sclerosis and normal volunteers effect of nabilone on nausea and vomiting after total abdominal hysterectomy. In the majority of pediatric palliative patients the treatment with dronabinol showed promising effects in treatment resistant spasticit. Sativex successfully treats neuropathic pain characterised by allodynia a randomised, double-blind, placebo-controlled clinical trial.
Marijuana an effective antiepileptic treatment in partial epilepsy? A case report and review of the literature. Comparison of bronchial effects of nabilone and terbutaline in healthy and asthmatic subjects. Thc reduced pain intensity and odynophagia (painful swallowing, in the mouth or oesophagus).
The impact of current cannabis use on general cognitive function in people with psychotic illness no difference in cognitive abilities between people with psychosis with and without cannabis use is cannabis use associated with various indices of motivation among adolescents? The mobile study-a phase iia enriched enrollment randomized withdrawal trial to assess the analgesic efficacy and safety of asp8477, a fatty acid amide hydrolase inhibitor, in patients with peripheral neuropathic pain. Patients with high ptsd scores were more likely to use cannabis to improve sleep, and for coping reasons more generally. Naef m, curatolo m, petersen-felix s, arendt-nielsen l, zbinden a, brenneisen r.
Smoked cannabis was well tolerated and effectively relieved chronic neuropathic pain from hiv-associated sensory neuropathy. Hindocha c, freeman tp, schafer g, gardener c, das rk, morgan cj, curran hv. Zajicek j, ball s, wright d, vickery j, nunn a, miller d, cano mg, mcmanus d, mallik s, hobart j on behalf of the cupid investigator group.
Carroll cb, bain pg, teare l, liu x, joint c, wroath c, parkin sg, fox p, wright d, hobart j, zajicek jp. A treatment with oral thc was associated with significant decreases in agitation, as well as improvements in sleep duration and appetite. Cannabis effective against pain due to epidermolysis bullosa according to case reports medical cannabis use by hodgkin lymphoma patients experience of a single center cannabinoids in attention-deficithyperactivity disorder a randomised-controlled trial cannabis and intractable chronic pain an explorative retrospective analysis of italian cohort of 614 patients cannabis may be effective in the treatment of chronic pain according to a large case series from italy a single dose of cannabidiol reduces blood pressure in healthy volunteers in a randomized crossover study cannabis and cognitive functioning in multiple sclerosis the role of gender cannabis use may have a negative effect on cognition in male patients with multiple sclerosis cannabis, tobacco, alcohol use, and the risk of early stroke a population-based cohort study of 45 000 swedish men cannabis use does not increase the risk of stroke in young people, while tobacco does potent immunomodulatory activity of a highly selective cannabinoid cb2 agonist on immune cells from healthy subjects and patients with multiple sclerosis moderate and vigorous physical activity patterns among marijuana users results from the 2007-2014 national health and nutrition examination surveys association of state recreational marijuana laws with adolescent marijuana use cerdб m, wall m, feng t, keyes km, sarvet a, schulenberg j, omalley pm, pacula rl, galea s, hasin ds how does marijuana affect outcomes after trauma in icu patients? A propensity-matched analysis singer m, azim a, okeeffe t, khan m, jain a, kulvatunyou n, gries l, jehan f, tang a, joseph b sativex oromucosal spray as adjunctive therapy in advanced cancer patients with chronic pain unalleviated by optimized opioid therapy two double-blind, randomized, placebo-controlled phase 3 studies.
Hazekamp a, grotenhermen f, abrams d, russo e, ware m, navarrete-varo r, brenneisen r, mьller-vahl k. A cannabis extract did not reduce pain in advanced cancer patients, who did not respond to opioids speechlessness in gilles de la tourette syndrome cannabis-based medicines improve severe vocal blocking tics in two patients speechlessness in tourette syndrome may be treated with cannabisthc according to case reports perioperative patient beliefs regarding potential effectiveness of marijuana (cannabinoids) for treatment of pain a prospective population survey cannabis use is more frequent among people with spinal cord injury than among the general population topical medical cannabis a new treatment for wound pain-three cases of pyoderma gangrenosum confirmed marijuana use and lymphocyte count in black people living with hiv delta-9-tetrahydrocannabinol-cannabidiol in the treatment of spasticity in chronic spinal cord injury a clinical experience cannabis may be helpful in patients with spinal cord injuries according to an observational study association between use of cannabis in adolescence and weight change into midlife association of cannabis use with the development of elevated anxiety symptoms in the general population a meta-analysis no relevant association between cannabis use and anxiety in the general population effect of food on the pharmacokinetics of dronabinol oral solution versus dronabinol capsules in healthy volunteers maximum blood concentrations after oral intake of thc were reached faster in a fasted state than in if taken together with a meal patient perceptions of the use of medical marijuana in the treatment of pain after musculoskeletal trauma a survey of patients at 2 trauma centers in massachusetts trauma patients find relief from a treatment with cannabis according to a survey cannabis use in people with parkinsons disease and multiple sclerosis a web-based investigation kindred jh, li k, ketelhut nb, proessl f, fling bw, honce jm, shaffer wr, rudroff t co-medication with cannabidiol may slow down the progression of motor neuron disease a case report cannabidiol slowed progression of amyotrophic lateral sclerosis in a case report evaluation of divided attention psychophysical task performance and effects on pupil sizes following smoked, vaporized and oral cannabis administration smoked marijuana attenuates performance and mood disruptions during simulated night shift work cannabis use and psychotic-like experiences trajectories during early adolescence the coevolution and potential mediators effect of continued cannabis use on medication adherence in the first two years following onset of psychosis schoeler t, petros n, di forti m, klamerus e, foglia e, murray r, bhattacharyya s heavy cannabis use may reduce adherence to medication in patients with psychosis effects on spasticity and neuropathic pain of an oral formulation of 9-tetrahydrocannabinol in patients with progressive multiple sclerosis. Less than one third of self-reported users mention a relief of their attacks following inhalation. Trevaskis nl, shackleford dm, charman wn, edwards ga, gardin a, appel-dingemanse s, kretz o, galli b, porter cj. Efficacy of two cannabis-based medicinal extracts for relief of central neuropathic pain from brachial plexus avulsion results of a randomised controlled trial berman j, lee j, cooper m, cannon a, sach j, mckerral s, taggart m, symonds c, fishel k, birch r analgesic effect of the synthetic cannabinoid ct-3 on chronic neuropathic pain a randomized controlled trial.
NIH Definition of Clinical Trial Case Studies | grants.nih.gov
The case studies provided below are designed to help you identify whether your study would be considered by NIH to be a clinical trial. Expect the case ...
Clinical Case Studies
Clinical Studies and Case Reports - cannabis med
Clinical Studies and Case Reports. On this site you will find clinical studies with cannabis or single cannabinoids in different diseases and case reports on the use ...
Clinical Case Studies
Clinical Studies and Case Reports. Medical cannabis use in post-traumatic stress disorder a naturalistic observational study.
Intestinal lymphatic transport enhances the post-prandial oral bioavailability of a novel cannabinoid receptor agonist via avoidance of first-pass metabolism. Objective ratings of opiate withdrawal decreased in patients using cannabis during stabilization a double-blind, placebo-controlled, crossover pilot trial with extension using an oral mucosal cannabinoid extract for treatment of chemotherapy-induced neuropathic pain.
Improvement in 4 of 6 participants, of whom 3 showed a significant improvement, Muller-vahl kr, schneider u, koblenz a, jobges m, kolbe h.
A medium dose of cannabis reduced pain, while a high dose increased pain induced by capsaicin oromucosal 9-tetrahydrocannabinolcannabidiol for neuropathic pain associated with multiple sclerosis an uncontrolled, open-label, 2-year extension trial. This is an open access journal which allows all content available freely without any charge to the individual user or any institution.
Journal of Clinical and Medical Case Studies - rroij.com
You may search for diseases (indications), authors, medication, study design (controlled study, open trial, case report etc. There was a synergistic effect between thc and morphine on the affective component of pain but not on the sensory component (9)-tetrahydrocannabinol and the opioid receptor agonist piritramide do not act synergistically in postoperative pain. Nabilone and metoclopramide were equally effective in reducing nausea and vomiting struwe m, kaempfer sh, geiger cj, pavia at, plasse tf, shepard kv, ries k, evans tg. The journal of clinical and medical case studies deals with publishing scientific information on case studies and reports. No differences in the number and type of adverse events were found, and no falls occurred after administration of thc.
Clinical experience with thccbd oromucosal spray in patients with multiple sclerosis-related spasticity. Results of a survey among australian patients, who treat themselves with cannabis self-reported effectiveness and safety of trokie lozenges a standardized formulation for the buccal delivery of cannabis extracts. A double-blind, controlled trial of nabilone vs. Thcv significantly decreased fasting plasma glucose and improved the function of cells in the pancreas improvement in seizures, stress was decreased, sleep improved and memoryconcentration was better effective treatment of spasticity using dronabinol in pediatric palliative care. Meiri e, jhangiani h, vredenburgh jj, barbato lm, carter fj, yang hm, baranowski v.
Frytak s, moertel cg, ofallon jr, rubin j, creagan et, oconnell mj, schutt aj, schwartau nw thc and pcp equally effective both better than placebo thc produced psychic effects in 82 delta-9-tetrahydrocannabinol as an antiemetic in cancer patients receiving high-dose methotrexate. Nabiximols as an agonist replacement therapy during cannabis withdrawal a randomized clinical trial allsop dj, copeland j, lintzeris n, dunlop aj, montebello m, sadler c, rivas gr, holland rm, muhleisen p, norberg mm, booth j, mcgregor is a double-blind, randomized, placebo-controlled, parallel group study of thccbd spray in peripheral neuropathic pain treatment significant improvements in pain, sleep quality and subjective evaluations of patients. Cannabinoid-induced effects on the nociceptive system a neurophysiological study in patients with secondary progressive multiple sclerosis. Single dose delta-9-tetrahydrocannabinol in chronic pancreatitis patients analgesic efficacy, pharmacokinetics and tolerability de vries m, van rijckevorsel dc, vissers kc, wilder-smith oh, van goor h( pain and nociception neuroscience research group no effect of a single low dose of thc on abdominal pain resulting from chronic pancreatitis in clinical study. Gorelick da, goodwin rs, schwilke e, schroeder jr, schwope dm, kelly dl, ortemann-renon c, bonnet d, huestis ma. German topical application of a cream with n-palmitoyl ethanolamine had a good antipruritic effect in most patients. White matter integrity in adolescents with histories of marijuana use and binge drinking. Levonantradol has analgetic activity but may have central nervous system adverse effects in humans. When both drugs were compared, both nausea and vomiting episodes were significantly lower in patients given nabilone. Cannabis use is associated with reduced prevalence of progressive stages of alcoholic liver disease.Welcome to the Journal . Medical Case studies are analyses of persons, diseases, decisions, periods, projects, or other systems that are studied concerning with ...
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Improvement of recognition of emotional facial affect by cbd and attenuation of the impairment induced by thc the effect of five day dosing with thcv on thc-induced cognitive, psychological and physiological effects in healthy male human volunteers a placebo-controlled, double-blind, crossover pilot trial. Use of medical marijuana for treatment of severe intractable nausea after laparoscopic roux-en-y gastric bypass surgery case report. A questionnaire survey of patients and carers of patients prescribed sativex as an unlicensed medicine. Smoked cannabis for spasticity in multiple sclerosis a randomized, placebo-controlled trial. Wallace m, schulteis g, atkinson jh, wolfson t, lazzaretto d, bentley h, gouaux b, abramson i Buy now Clinical Case Studies
In more than 80 improvement of spasticity, pain, tremor, depression, anxiety, and paresthesia intractable nausea and vomiting due to gastrointestinal mucosal metastases relieved by tetrahydrocannabinol (dronabinol). Randomised, double-blind, placebo-controlled trial to assess the potential of cannabinoid receptor stimulation in the treatment of dystonia. Improvement in behaviour and alertness, language, communication, motor skills and sleep evaluating sativex in neuropathic pain management a clinical and neurophysiological assessment in multiple sclerosis. Impact of cannabis treatment on the quality of life, weight and clinical disease activity in inflammatory bowel disease patients a pilot prospective study Clinical Case Studies Buy now
Tetrahydrocannabinol does not reduce pain in patients with chronic abdominal pain in a phase 2 placebo-controlled study. Survey on cannabis use in parkinsons disease subjective improvement of motor symptoms. White matter integrity in adolescents with histories of marijuana use and binge drinking. Cannabinoids reduce levodopa-induced dyskinesia in parkinsons disease a pilot study. Chang ae, shiling dj, stillman rc, goldberg nh, seipp ca, barofsky i, rosenberg no significant reduction of the number of vomiting, volume of emesis, degree of nausea, or duration of nausea dose vs response of tetrahydroannabinol (thc) vs prochlorperazine as chemotherapy antiemetics.
Application of thc reduced the need of an opioid to treat postoperative pain but the difference to placebo was not significant dronabinol for supportive therapy in patients with malignant melanoma and liver metastases Buy Clinical Case Studies at a discount
Dronabinol - eine mцgliche neue therapieoption bei copd-patienten mit pulmonaler kachexie dronabinol, a possible new therapeutic option in patients with copd and pulmonal cachexia delta-9-tetrahydrocannabinol effects in schizophrenia implications for cognition, psychosis, and addiction. Symptom scores were significantly better for patients on nabilone for nausea, retching and vomiting. Beneficial effects of cannabis on spasticity in ms seem to be maintained over long-term treatment, with no evidence of tolerance. Chang ae, shiling dj, stillman rc, goldberg nh, seipp ca, barofsky i, simon rm, rosenberg sa. The effects of the cannabinoid receptor agonist nabilone on l-dopa induced dyskinesia in patients with idiopathic parkinsons disease (pd) Buy Online Clinical Case Studies
Fatty acid amide hydrolase inhibitor treatment in men with chronic prostatitischronic pelvic pain syndrome an adaptive double-blind, randomized controlled trial. On this site you will find clinical studies with cannabis or single cannabinoids in different diseases and case reports on the use of cannabis by patients. Comparison of analgesic effects and patient tolerability of nabilone and dihydrocodeine for chronic neuropathic pain randomised, crossover, double blind study. Physiologic observations in a controlled clinical trial of the antiemetic effectiveness of 5, 10, and 15 mg of delta 9-tetrahydrocannabinol in cancer chemotherapy. Mitigation of post-traumatic stress symptoms by cannabis resin a review of the clinical and neurobiological evidence Buy Clinical Case Studies Online at a discount
Smoked cannabis was well tolerated and effectively relieved chronic neuropathic pain from hiv-associated sensory neuropathy. Urinary urgency, the number and volume of incontinence episodes, frequency and nocturia all decreased. Beneficial effects of cannabis on spasticity in ms seem to be maintained over long-term treatment, with no evidence of tolerance. The natural cannabinoid tetrahydrocannabivarin (thcv) altered the nerve response to pleasant and unpleasant stimuli in a way that it suggests therapeutic activity in obesity. Patients with high ptsd scores were more likely to use cannabis to improve sleep, and for coping reasons more generally.
Thc reduced intraoculat pressure and improved blood circulation in the retina Clinical Case Studies For Sale
A double-blind trial of delta 9-tetrahydrocannabinol in primary anorexia nervosa. Thc reduces neuropathic pain and this is associated with altered connections between two brain regions association between the detection of alcohol, illicit drugs andor psychotropic medicationsopioids in patients admitted due to trauma and trauma recidivism a cohort study. Users are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without any prior permission from the publisher or the author provided the author is given due credit wherever necessary. Jadoon ka, ratcliffe sh, barrett da, thomas el, stott c, bell jd, osullivan se, tan gd For Sale Clinical Case Studies
Marijuana smoking does not accelerate progression of liver disease in hiv-hepatitis c coinfection a longitudinal cohort analysis cannabis does not increase the risk of liver fibrosis in patients co-infected with hiv and hcv cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia leweke fm, piomelli d, pahlisch f, muhl d, gerth cw, hoyer c, klosterkцtter j, hellmich m, koethe d. Marijuana an effective antiepileptic treatment in partial epilepsy? A case report and review of the literature. Dronabinol - eine mцgliche neue therapieoption bei copd-patienten mit pulmonaler kachexie dronabinol, a possible new therapeutic option in patients with copd and pulmonal cachexia delta-9-tetrahydrocannabinol effects in schizophrenia implications for cognition, psychosis, and addiction Sale Clinical Case Studies
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